学生姝被内谢出白浆,精品免费囯产一区二区三区四区,全肉变态重口调教高辣小说,国产偷v国产偷v亚洲高清学生

熱門搜索: 硫酸角質(zhì)素(KS)ELISA試劑盒(種屬:魚) 白介素6(IL6)ELISA試劑盒(種屬:魚) 魚白介素10(IL10)ELISA試劑盒發(fā)貨及時 斑馬魚白介素12BELISA試劑盒發(fā)貨及時 兔載脂蛋白B(apo-B)ELISA試劑盒發(fā)貨及時 兔孕酮(PROG)ELISA試劑盒發(fā)貨及時 兔羥脯氨酸(Hyp)ELISA試劑盒發(fā)貨及時 兔抗酒石酸酸性磷酸酶ELISA試劑盒發(fā)貨及時 兔晶體蛋白α(Cryα)ELISA試劑盒發(fā)貨及時 兔結(jié)締組織生長因子ELISA試劑盒發(fā)貨及時 兔基質(zhì)金屬蛋白酶9ELISA試劑盒發(fā)貨及時 兔肺表面活性物質(zhì)相ELISA試劑盒發(fā)貨及時 CD206分子ELISA試劑盒(種屬:小鼠) CC趨化因子受體6ELISA試劑盒(種屬:小鼠) 阻抑素(PHB)ELISA試劑盒(種屬:大鼠) 中性內(nèi)肽酶;腦啡ELISA試劑盒(種屬:大鼠)

技術(shù)文章/ Technical Articles

您的位置:首頁  /  技術(shù)文章  /  引用大鼠ELISA科研檢測試劑盒的文獻

引用大鼠ELISA科研檢測試劑盒的文獻

更新時間:2023-09-19      瀏覽次數(shù):1206

引用大鼠ELISA科研檢測試劑盒的文獻


文獻收集:

Epimedium Aqueous Extract Ameliorates Cerebral Ischemia/Reperfusion Injury through Inhibiting ROS/NLRP3- Mediated Pyroptosis

引用試劑盒:

種屬:大鼠

IL-1β (RJ15465), IL-18 (RJ15463),TNF-α (RJ16622), IL-6 (RJ15478), IL-10 (RJ15453),iNOS(RJ16565) , MDA (RJ15503), ROS(RJ15780) ,CAT(RJ15737),SOD(RJ16691) ,GSHPx(RJ25745) , LDH (RJ16172)

 

638272614877654132225.jpg

IF:7.675


Abstract: Cerebral ischemia/reperfusion causes exacerbated neuronal damage involving excessive neuroinflammation and oxidative stress. ROS is considered a signal molecule to activate NLRP3; thus, the ROS/NLRP3/pyroptosis axis plays a vital role in the pathogenesis of cerebral ischemia/reperfusion injury (CIRI). Therefore, targeting the inhibition of the ROS/NLRP3/pyroptosis axis may be a promising therapeutic tactic for CIRI. Epimedium (EP) contains many active ingredients (ICA, ICS II, and ICT), which have a wide range of pharmacological activities. However, whether EP can protect against CIRI remains unknown. Thus, in this study, we designed to investigate the effect and possible underlying mechanism of EP on CIRI. The results showed that treatment with EP dramatically mitigated brain damage in rats following CIRI, which was achieved by suppressing mitochondrial oxidative stress and neuroinflammation. Furthermore, we identified the ROS/NLRP3/pyroptosis axis as a vital process and NLRP3 as a vital target in EP-mediated protection. Most interestingly, the main compounds of EP directly bonded with NLRP3, as reflected by molecular docking, which indicated that NLRP3 might be a promising therapeutic target for EP-elicited cerebral protection. In conclusion, our findings illustrate that ICS II protects against neuron loss and neuroinflammation after CIRI by inhibiting ROS/NLRP3-mediated pyroptosis.


image.png









微信掃一掃

郵箱:2450868877@qq.com

傳真:86-區(qū)號-傳真號碼

地址:上海市楊浦區(qū)鐵嶺路32號1519-10室

Copyright © 2025 上海仁捷生物科技有限公司版權(quán)所有   備案號:滬ICP備16052159號-1   總訪問量:298997   技術(shù)支持:化工儀器網(wǎng)

TEL:17302193538

掃碼加微信
一边吃奶一边做爰| china贵州少妇video| 特大欧美黑人巨大xxoo| 午夜无码熟熟妇丰满人妻| 亚洲综合久久日日躁综合| 嫩模超大胆大尺度人体写真| 欧美另类丰满熟妇乱xxxxx| 狠狠躁夜夜躁人人爽野战天天| 国内精品久久毛片一区二区| 绝伦の上司に一晚人妻| 娇妻在客厅被朋友玩得呻吟动漫| 国产精品99无码一区二区| 丰满多毛的大隂户视频中国| 无码国产精品一区二区免费16| 一本色道久久hezyo无码| 少妇沦陷精油按摩中文字幕| 亚洲精品无码高潮喷水a片小说| 亚洲欧美自偷自拍另类视| 色戒2小时38分在线观看| 国产偷v国产偷v亚洲高清| 久久久国产精品人人片| 午夜亚洲福利在线老司机| 草莓视频app黄| 少妇bbwbbw性生话| 色一情一区二| 日本无翼乌邪恶彩色大全| 中文字幕丰满乱孑伦无码专区| 玩弄了裸睡少妇人妻野战| 久久国产精品偷| 少妇人妻偷人精品一区二区| 偷国精产品久拍自产| 女人被添全过程a片试看v| 久久久亚洲av波多野结衣| 啊轻点灬太粗嗯太深了| 村长用力挺进她的花苞啥电视| 狂躁女人双腿流白色液体| 两腿间花蒂被吸得肿了视频| 久久精品人人做人人爽电影蜜月| 51精产一二三产区区别| 驯服人妻hd中字日本| 欧美在线观看|